Chronic Respiratory Disease (CRD) is a long-term chronic condition which persist for a long period of time. It is defined by persistent infection of chronic coughing. It is generally non-reversible and often slowly progressive. It affects the respiratory tract, nasal passage and lungs. It is caused with Mycoplasma gallisepticum which affect respiratory system. The sign of CRD are sniffing, sneezing, coughing and other respiratory disease. It heavily affects the health of the body. To overcome from this there is a need of treatment which can cure this problem. There is a need of antibiotic that can help to control this, but reducing stress is the main priority in managing the disease. P-cold is one of the best immunity modulators and CRD medicine which can cure all types of these health problems. It is a herbal medicine which is a potent blend of herbal extracts of berberis arista, vitis vinifera, olea europea with fortified vitamins. It benefits the body in many ways.